Carotid plaque thickness is increased in chronic kidney disease and associated with carotid and coronary calcification.

ABSTRACT:

Background

Chronic kidney disease accelerates both atherosclerosis and arterial calcification. The aim of the present study was to explore whether maximal carotid plaque thickness (cPTmax) was increased in patients with chronic kidney disease compared to controls and associated with cardiovascular disease and severity of calcification in the carotid and coronary arteries.

Methods

The study group consisted of 200 patients with chronic kidney disease stage 3 from the Copenhagen Chronic Kidney Disease Cohort and 121 age- and sex-matched controls. cPTmax was assessed by ultrasound and arterial calcification by computed tomography scanning.

Results

Carotid plaques were present in 58% of patients (n = 115) compared with 40% of controls (n = 48), p = 0.002. Among participant

SUBMITTER: Bjergfelt SS 

PROVIDER: S-EPMC8610240 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature