Epidemiology of Clostridioides difficile in South Africa.

ABSTRACT:

Background

Clostridioides difficile (CD) is the most common healthcare-associated enteric infection. There is currently limited epidemiological evidence on CD incidence in South Africa.

Aim

To estimate the burden of CD infection (CDI) in the South African public sector between 1 July 2016 and 30 June 2017.

Methods

A retrospective cohort study utilizing secondary data was conducted to describe the epidemiology of CD in South Africa. We assessed the patient-level association between variables of interest, CD, and CD recurrence, by undertaking both univariate and multivariable analysis. Adjusted incidence rate ratios (aIRR) were calculated utilizing multivariable Poisson regression. The incidence of CD, CD recurrence and CD testing was estimated by Poisson regression for

SUBMITTER: de Jager P 

PROVIDER: S-EPMC8610264 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature