Multi-functional bioactive secondary metabolites derived from endophytic fungi of marine algal origin.

ABSTRACT: Endophytic fungi from marine macroalgae are endowed with various pharmacologically active metabolites. This study mined, identified and screened endophytic fungi (EF) isolated from marine algae from the west coast of South India for screening anticancer, antioxidant and antimicrobial secondary metabolite producers. Five EF isolated from sampled marine algae were identified using morphology and ITS based identification as Grammothele fuligo, Rigidoporus vinctus, Cystobasidium minutum, Candida railenensis and Pichia kudriavzevii. After culturing 20 days on PDA medium, the ethyl acetate extracts of Cystobasidium minutum showed potent antimicrobial activity against P. aeruginosa with an IC₅₀ value of 458.7 ± 1.021 µg/mL whereas Pichia kudriavzevii

SUBMITTER: M H 

PROVIDER: S-EPMC8610299 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature