Viability assessment of human peripheral blood-derived stem cells after three methods of nebulization.

ABSTRACT:

Background and objectives

Drug delivery by nebulization has become a crucial strategy for treating different respiratory and lung diseases. Emerging evidence implicates stem cell therapy as a promising tool in treating such conditions, not only by alleviating the related symptoms but by improving the prognosis. However, delivery of human peripheral blood-derived stem cells (hPBSCs) to the respiratory airways remains an innovative approach yet to be realized. This study is an analytic, translational, and in vitro research to assess the viability and morphological changes of identified cell populations in hPBSCs cocktail derived from COVID-19 patients.

Methods and results

Peripheral blood (PB) samples were obtained from patients enrolled in the SENTAD-COVID Study (Clini

SUBMITTER: Castillo Aleman YM 

PROVIDER: S-EPMC8610807 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature