The influence of biological age and sex on long-term outcome after percutaneous coronary intervention for ST-elevation myocardial infarction.

ABSTRACT:

Background

Outcome following ST-segment elevation myocardial infarction (STEMI) is thought to be worse in women than in age-matched men. We assessed whether such differences occur in the UK Pan-London dataset and if age, and particularly menopause, influences upon outcome.

Methods

We undertook an observational cohort study of 26,799 STEMI patients (20,633 men, 6,166 women) between 2005-2015 at 8 centres across London, UK. Patient details were recorded at the time of the procedure into local databases using the British Cardiac Intervention Society (BCIS) PCI dataset. Primary outcome was all-cause mortality at a median follow-up of 4.1 years (IQR: 2.2-5.8 years).

Results

Kaplan-Meier analysis demonstrated a higher mortality rate in women versus men (15.6% men vs. 25.3%

SUBMITTER: Rathod KS 

PROVIDER: S-EPMC8611266 | biostudies-literature | 2021

REPOSITORIES: biostudies-literature