Miller Fisher syndrome following Pfizer COVID-19 vaccine.

ABSTRACT:

Introduction

Miller Fisher syndrome (MFS) is a rare variant of Guillain-Barre syndrome characterized by ataxia, areflexia, and ophthalmoplegia. We present a case of MFS following Pfizer COVID-19 vaccine.

Case presentation

A previously healthy 24-year-old female presented with binocular horizontal diplopia 18 days after receiving the first dose of Pfizer COVID-19 vaccine (Comirnaty®). Anti-ganglioside testing revealed positive anti-GQ1b antibodies. Intravenous immunoglobulins were administered, in a dose of 2 g per kg of body weight over 5 days. On a follow-up exam 3 weeks after the treatment, clinical improvement was noted with normal bulbomotor examination.

Conclusion

Patients with acute ophthalmoplegia occurring after COVID-19 vaccination should be screened for the

SUBMITTER: Abicic A 

PROVIDER: S-EPMC8611397 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature