Room-Temperature Cu(II) Radical-Triggered Alkyne C-H Activation.

ABSTRACT: A dimeric Cu(II) complex [Cu(II)₂L₂(μ₂-Cl)Cl] (1) built from an asymmetric tridentate ligand (2-(((2-aminocyclohexyl)imino)methyl)-4,6-di-tert-butylphenol) and weakly coordinating anions has been synthesized and structurally characterized. In dichloromethane solution, 1 exists in a monomeric [Cu(II)LCl] (1') (85%)-dimeric (1) (15%) equilibrium, and cyclic voltammetry (CV) and electron paramagnetic resonance (EPR) studies indicate structural stability and redox retention. Addition of phenylacetylene to the CH₂Cl₂ solution populates 1' and leads to the formation of a transient radical species. Theoretical studies support this notion and show that the radical initiates an alkyne C-H bond activatio

SUBMITTER: Devonport J 

PROVIDER: S-EPMC8611675 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature