Characterising the relationships between physiological indicators and all-cause mortality (NHANES): a population-based cohort study.

ABSTRACT:

Background

Mortality risk stratification based on dichotomising a physiological indicator with a cutoff point might not adequately capture increased mortality risk and might not account for non-linear associations. We aimed to characterise the linear and non-linear relationships of 27 physiological indicators with all-cause mortality to evaluate whether the current clinical thresholds are suitable in distinguishing patients at high risk for mortality from those at low risk.

Methods

For this observational cohort study of the US non-institutionalised population, we used data from adults (≥18 years) included in the 1999-2014 National Health and Nutrition Examination Survey (NHANES) linked with National Death Index mortality data collected from Jan 1, 1999, up until Dec 31, 2015

SUBMITTER: Nguyen VK 

PROVIDER: S-EPMC8612451 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature