Thalamocortical functional connectivity in patients with insomnia using resting-state fMRI.

ABSTRACT:

Background

Insomnia is a common disorder that affects a vast number of patients; the hyperarousal theory of insomnia postulates that patients with insomnia are physiologically activated not only at nighttime but also during the daytime. We aimed to investigate the differences in the resting-state functional connectivity (RSFC) of the thalamus with cortical areas between patients with insomnia disorder and healthy controls.

Methods

All participants completed clinical questionnaires and underwent portable polysomnography and resting-state fMRI.

Results

Patients in the insomnia group (n = 50) showed increased RSFC between the thalamus and right medial superior frontal area, bilateral middle temporal areas, left rectus and right parahippocampal areas compared with

SUBMITTER: Kim N 

PROVIDER: S-EPMC8612467 | biostudies-literature | 2021 Nov-Dec

REPOSITORIES: biostudies-literature