Chronic Limb Remote Ischemic Conditioning may have an Antihypertensive Effect in Patients with Hypertension.

ABSTRACT: Hypertension is the leading preventable risk factor for all-cause morbidity and mortality worldwide. Despite antihypertensive medications have been available for decades, a big challenge we are facing is to increase the blood pressure (BP) control rate among the population. Therefore, it is necessary to search for new antihypertensive means to reduce the burden of disease caused by hypertension. Limb remote ischemic conditioning (LRIC) can trigger endogenous protective effects through transient and repeated ischemia on the limb to protect specific organs and tissues including the brain, heart, and kidney. The mechanisms of LRIC involve the regulation of the autonomic nervous system, releasing humoral factors, improvement of vascular endothelial function, and modulation of immune/inflammato

SUBMITTER: Guo W 

PROVIDER: S-EPMC8612623 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature