Regulation of prophage induction and lysogenization by phage communication systems.

ABSTRACT: Many viruses cause both lytic infections, where they release viral particles, and dormant infections, where they await future opportunities to reactivate.¹ The benefits of each transmission mode depend on the density of susceptible hosts in the environment.^2-4 Some viruses infecting bacteria use molecular signaling to respond plastically to changes in host availability.⁵ These viruses produce a signal during lytic infection and regulate, based on the signal concentration in the environment, the probability with which they switch to causing dormant infections.^5,6 We present an analytical framework to examine the adaptive significance of plasticity in viral life-history traits in fluctuating environments. Our model generalizes

SUBMITTER: Bruce JB 

PROVIDER: S-EPMC8612742 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature