Nationwide effectiveness of five SARS-CoV-2 vaccines in Hungary-the HUN-VE study.

ABSTRACT:

Objectives

The Hungarian vaccination campaign was conducted with five different vaccines during the third wave of the coronavirus disease 2019 (COVID-19) pandemic in 2021. This observational study (HUN-VE: Hungarian Vaccine Effectiveness) estimated vaccine effectiveness against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection and COVID-19-related mortality in 3.7 million vaccinated individuals.

Methods

Incidence rates of SARS-CoV-2 infection and COVID-19-related mortality were calculated using data from the National Public Health Centre surveillance database. Estimated vaccine effectiveness was calculated as 1 - incidence rate ratio ≥7 days after the second dose for each available vaccine versus an unvaccinated control group using mixed-effect negative

SUBMITTER: Voko Z 

PROVIDER: S-EPMC8612758 | biostudies-literature | 2022 Mar

REPOSITORIES: biostudies-literature