Cold-induced Arabidopsis FRIGIDA nuclear condensates for FLC repression.

ABSTRACT: Plants use seasonal temperature cues to time the transition to reproduction. In Arabidopsis thaliana, winter cold epigenetically silences the floral repressor locus FLOWERING LOCUS C (FLC) through POLYCOMB REPRESSIVE COMPLEX 2 (PRC2)¹. This vernalization process aligns flowering with spring. A prerequisite for silencing is transcriptional downregulation of FLC, but how this occurs in the fluctuating temperature regimes of autumn is unknown^2-4. Transcriptional repression correlates with decreased local levels of histone H3 trimethylation at K36 (H3K36me3) and H3 trimethylation at K4 (H3K4me3)^5,6, which are deposited during FRIGIDA (FRI)-dependent activation of FLC^7-10. Here we show that cold rapidly promotes the formation of FRI nuclear condensate

SUBMITTER: Zhu P 

PROVIDER: S-EPMC8612926 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature