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Associations between sleep disturbances, diabetes and mortality in the UK Biobank cohort: A prospective population-based study.


ABSTRACT: Non-communicable diseases, including diabetes, are partly responsible for the deceleration of improvements of life expectancy in many countries. Diabetes is also associated with sleep disturbances. Our aim was to determine whether sleep disturbances, particularly in people with diabetes, were associated with increased mortality risk. Data from the UK Biobank were analysed (n = 487,728, mean follow-up time = 8.9 years). The primary exposure was sleep disturbances, assessed through the question: Do you have trouble falling asleep at night or do you wake up in the middle of the night? The primary outcome was mortality. We also dichotomized sleep disturbances into "never/sometimes" versus "usually" (frequently), and combined with the presence/absence of diabetes: 24.2% of participants reported

SUBMITTER: von Schantz M 

PROVIDER: S-EPMC8612946 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature