A ROR2 coding variant is associated with craniofacial variation in domestic pigeons.

ABSTRACT: Vertebrate craniofacial morphogenesis is a highly orchestrated process that is directed by evolutionarily conserved developmental pathways.^1,2 Within species, canalized development typically produces modest morphological variation. However, as a result of millennia of artificial selection, the domestic pigeon displays radical craniofacial variation within a single species. One of the most striking cases of pigeon craniofacial variation is the short-beak phenotype, which has been selected in numerous breeds. Classical genetic experiments suggest that pigeon beak length is regulated by a small number of genetic factors, one of which is sex linked (Ku2 locus).^3-5 However, the genetic underpinnings of pigeon craniofacial variation remain unknown. Usi

SUBMITTER: Boer EF 

PROVIDER: S-EPMC8612976 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature