Polarization sensitive optical coherence tomography with single input for imaging depth-resolved collagen organizations.

ABSTRACT: Collagen organization plays an important role in maintaining structural integrity and determining tissue function. Polarization-sensitive optical coherence tomography (PSOCT) is a promising noninvasive three-dimensional imaging tool for mapping collagen organization in vivo. While PSOCT systems with multiple polarization inputs have demonstrated the ability to visualize depth-resolved collagen organization, systems, which use a single input polarization state have not yet demonstrated sufficient reconstruction quality. Herein we describe a PSOCT based polarization state transmission model that reveals the depth-dependent polarization state evolution of light backscattered within a birefringent sample. Based on this model, we propose a polarization state tracing method that relies on a disc

SUBMITTER: Tang P 

PROVIDER: S-EPMC8613400 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature