Characterizing Long COVID: Deep Phenotype of a Complex Condition.

ABSTRACT:

Background

Numerous publications describe the clinical manifestations of post-acute sequelae of SARS-CoV-2 (PASC or "long COVID"), but they are difficult to integrate because of heterogeneous methods and the lack of a standard for denoting the many phenotypic manifestations. Patient-led studies are of particular importance for understanding the natural history of COVID-19, but integration is hampered because they often use different terms to describe the same symptom or condition. This significant disparity in patient versus clinical characterization motivated the proposed ontological approach to specifying manifestations, which will improve capture and integration of future long COVID studies.

Methods

The Human Phenotype Ontology (HPO) is a widely used standard for exchange

SUBMITTER: Deer RR 

PROVIDER: S-EPMC8613500 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature