IMUP and GPRC5A: two newly identified risk score indicators in pancreatic ductal adenocarcinoma.

ABSTRACT:

Background

Pancreatic cancer has been a threateningly lethal malignant tumor worldwide. Despite the promising survival improvement in other cancer types attributing to the fast development of molecular precise medicine, the current treatment situation of pancreatic cancer is still woefully challenging since its limited response to neither traditional radiotherapy and chemotherapy nor emerging immunotherapy. The study is to explore potential responsible genes during the development of pancreatic cancer, thus identifying promising gene indicators and probable drug targets.

Methods

Different bioinformatic analysis were used to interpret the genetic events in pancreatic cancer development. Firstly, based on multiple cDNA microarray profiles from Gene Expression Omnibus (GEO) dat

SUBMITTER: Wei R 

PROVIDER: S-EPMC8613923 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature