Motion-corrected and high-resolution anatomically assisted (MOCHA) reconstruction of arterial spin labeling MRI.

ABSTRACT:

Purpose

A model-based reconstruction framework is proposed for motion-corrected and high-resolution anatomically assisted (MOCHA) reconstruction of arterial spin labeling (ASL) data. In this framework, all low-resolution ASL control-label pairs are used to reconstruct a single high-resolution cerebral blood flow (CBF) map, corrected for rigid-motion, point-spread-function blurring and partial volume effect.

Methods

Six volunteers were recruited for CBF imaging using pseudo-continuous ASL labeling, two-shot 3D gradient and spin-echo sequences and high-resolution T₁ -weighted MRI. For 2 volunteers, high-resolution scans with double and triple resolution in the partition direction were additionally collected. Simulations were designed for evaluations against a high-r

SUBMITTER: Mehranian A 

PROVIDER: S-EPMC8614125 | biostudies-literature | 2020 Sep

REPOSITORIES: biostudies-literature