Chitosan Enhances the Anti-Biofilm Activity of Biodentine against an Interkingdom Biofilm Model.

ABSTRACT: Endodontic infection is a biofilm disease that is difficult to irradicate with current treatment protocols, and as such, persistent micro-organisms may lead to ongoing or recurrent disease. The potential for the use of enhanced filling materials to modify biofilm regrowth is a promising strategy. This current study aimed to evaluate the anti-biofilm efficacy of calcium silicate cements modified with chitosan. The development of mono-species and multi-species biofilms on ProRoot MTA, Biodentine and bovine dentine discs were explored using quantitative microbiology analysis. The effect on regrowth of biofilms was assessed following the addition of chitosan to each cement. In comparison to a dentine substrate, both materials did not show the ability to inhibit biofilm regrowth. Biodentine inc

SUBMITTER: Abusrewil S 

PROVIDER: S-EPMC8614659 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature