Novel Vaccine Adjuvants as Key Tools for Improving Pandemic Preparedness.

ABSTRACT: Future infectious disease outbreaks are inevitable; therefore, it is critical that we maximize our readiness for these events by preparing effective public health policies and healthcare innovations. Although we do not know the nature of future pathogens, antigen-agnostic platforms have the potential to be broadly useful in the rapid response to an emerging infection-particularly in the case of vaccines. During the current COVID-19 pandemic, recent advances in mRNA engineering have proven paramount in the rapid design and production of effective vaccines. Comparatively, however, the development of new adjuvants capable of enhancing vaccine efficacy has been lagging. Despite massive improvements in our understanding of immunology, fewer than ten adjuvants have been approved for human use in

SUBMITTER: Pogostin BH 

PROVIDER: S-EPMC8615241 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature