Functional Role of AKNA: A Scoping Review.

ABSTRACT: Human akna encodes an AT-hook transcription factor whose expression participates in various cellular processes. We conducted a scoping review on the literature regarding the functional role of AKNA according to the evidence found in human and in vivo and in vitro models, stringently following the "PRISMA-ScR" statement recommendations.

Methods

We undertook an independent PubMed literature search using the following search terms, AKNA OR AKNA ADJ gene OR AKNA protein, human OR AKNA ADJ functions. Observational and experimental articles were considered. The selected studies were categorized using a pre-determined data extraction form. A narrative summary of the evidence was produced.

Results

AKNA modulates the expression of CD40 and CD40L genes in immune system cells. It

SUBMITTER: Ramirez-Gonzalez A 

PROVIDER: S-EPMC8615511 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature