Long-Term Consequences of Placental Vascular Pathology on the Maternal and Offspring Cardiovascular Systems.

ABSTRACT: Over the last thirty years, evidence has been accumulating that Hypertensive Disorders of Pregnancy (HDP) and, specifically, Preeclampsia (PE) produce not only long-term effects on the pregnant woman, but have also lasting consequences for the fetus. At the core of these consequences is the phenomenon known as defective deep placentation, being present in virtually every major obstetrical syndrome. The profound placental vascular lesions characteristic of this pathology can induce long-term adverse consequences for the pregnant woman's entire arterial system. In addition, placental growth restriction and function can, in turn, cause a decreased blood supply to the fetus, with long-lasting effects. Women with a history of HDP have an increased risk of Cardiovascular Diseases (CVD) compared

SUBMITTER: Benagiano M 

PROVIDER: S-EPMC8615676 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature