Effective Connectivity during an Avoidance-Based Pavlovian-to-Instrumental Transfer Task.

ABSTRACT: Pavlovian-to-instrumental transfer (PIT) refers to a phenomenon whereby a classically conditioned stimulus (CS) impacts the motivational salience of instrumental behavior. We examined behavioral response patterns and functional magnetic resonance imaging (fMRI) based effective connectivity during an avoidance-based PIT task. Eleven participants (8 females; M_age = 28.2, SD = 2.8, range = 25-32 years) completed the task. Effective connectivity between a priori brain regions engaged during the task was determined using hemodynamic response function group iterative multiple model estimation (HRF-GIMME). Participants exhibited behavior that was suggestive of specific PIT, a CS previously associated with a reinforcing outcome increased instrumental responding dire

SUBMITTER: Petrie DJ 

PROVIDER: S-EPMC8615846 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature