The Protein Landscape of Mucinous Ovarian Cancer: Towards a Theranostic.

ABSTRACT: MOC is a rare histotype of epithelial ovarian cancer, and current management options are inadequate for the treatment of late stage or recurrent disease. A shift towards personalised medicines in ovarian cancer is being observed, with trials targeting specific molecular pathways, however, MOC lags due to its rarity. Theranostics is a rapidly evolving category of personalised medicine, encompassing both a diagnostic and therapeutic approach by recognising targets that are expressed highly in tumour tissue in order to deliver a therapeutic payload. The present review evaluates the protein landscape of MOC in recent immunohistochemical- and proteomic-based research, aiming to identify potential candidates for theranostic application. Fourteen proteins were selected based on cell membrane loca

SUBMITTER: Youssef A 

PROVIDER: S-EPMC8616050 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature