Prediction of protein assemblies, the next frontier: The CASP14-CAPRI experiment.

ABSTRACT: We present the results for CAPRI Round 50, the fourth joint CASP-CAPRI protein assembly prediction challenge. The Round comprised a total of twelve targets, including six dimers, three trimers, and three higher-order oligomers. Four of these were easy targets, for which good structural templates were available either for the full assembly, or for the main interfaces (of the higher-order oligomers). Eight were difficult targets for which only distantly related templates were found for the individual subunits. Twenty-five CAPRI groups including eight automatic servers submitted ~1250 models per target. Twenty groups including six servers participated in the CAPRI scoring challenge submitted ~190 models per target. The accuracy of the predicted models was evaluated using the classical CAPRI c

SUBMITTER: Lensink MF 

PROVIDER: S-EPMC8616814 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature