Correlates of plasma concentrations of per- and poly-fluoroalkyl substances among reproductive-aged Black women.

ABSTRACT:

Background

Per- and polyfluoroalkyl substances (PFAS) are synthetic chemicals used in commercial and consumer goods. Black women are underrepresented in studies of PFAS exposure.

Methods

We performed a cross-sectional analysis of correlates of plasma PFAS concentrations among 1499 Black women aged 23-35 participating in the Study of Environment, Lifestyle, and Fibroids (SELF), a Detroit-based cohort study. At baseline (2010-2012), participants provided questionnaire data on socio-demographics; behaviors; diet; and menstrual, contraceptive, and reproductive histories. Using mass spectrometry in non-fasting plasma samples collected at enrollment, we quantified several PFAS, including perfluorohexane sulfonate (PFHxS), perfluorooctane sulfonate (PFOS), perfluorooctanoate (PFOA)

SUBMITTER: Wise LA 

PROVIDER: S-EPMC8616815 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature