Cardiovascular ¹⁸F-fluoride positron emission tomography-magnetic resonance imaging: A comparison study.

ABSTRACT:

Background

¹⁸F-Fluoride uptake denotes calcification activity in aortic stenosis and atherosclerosis. While PET/MR has several advantages over PET/CT, attenuation correction of PET/MR data is challenging, limiting cardiovascular application. We compared PET/MR and PET/CT assessments of ¹⁸F-fluoride uptake in the aortic valve and coronary arteries.

Methods and results

18 patients with aortic stenosis or recent myocardial infarction underwent ¹⁸F-fluoride PET/CT followed immediately by PET/MR. Valve and coronary ¹⁸F-fluoride uptake were evaluated independently. Both standard (Dixon) and novel radial GRE) MR attenuation correction (AC) maps were validated against PET/CT with results expressed as tissue-to-background ratios (TBRs). Vis

SUBMITTER: Andrews JPM 

PROVIDER: S-EPMC8616877 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature