Ontology highlight
ABSTRACT:
SUBMITTER: Heinemann KJ
PROVIDER: S-EPMC8616923 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Heinemann Katharina J KJ Yang Sun-Young SY Straube Henryk H Medina-Escobar Nieves N Varbanova-Herde Marina M Herde Marco M Rhee Sangkee S Witte Claus-Peter CP
Nature communications 20211125 1
In plants, guanosine monophosphate (GMP) is synthesized from adenosine monophosphate via inosine monophosphate and xanthosine monophosphate (XMP) in the cytosol. It has been shown recently that the catabolic route for adenylate-derived nucleotides bifurcates at XMP from this biosynthetic route. Dephosphorylation of XMP and GMP by as yet unknown phosphatases can initiate cytosolic purine nucleotide catabolism. Here we show that Arabidopsis thaliana possesses a highly XMP-specific phosphatase (XMP ...[more]