Mechanisms of oxygenation responses to proning and recruitment in COVID-19 pneumonia.

ABSTRACT:

Purpose

This study aimed at investigating the mechanisms underlying the oxygenation response to proning and recruitment maneuvers in coronavirus disease 2019 (COVID-19) pneumonia.

Methods

Twenty-five patients with COVID-19 pneumonia, at variable times since admission (from 1 to 3 weeks), underwent computed tomography (CT) lung scans, gas-exchange and lung-mechanics measurement in supine and prone positions at 5 cmH₂O and during recruiting maneuver (supine, 35 cmH₂O). Within the non-aerated tissue, we differentiated the atelectatic and consolidated tissue (recruitable and non-recruitable at 35 cmH₂O of airway pressure). Positive/negative response to proning/recruitment was defined as increase/decrease of PaO₂/FiO₂. Appare

SUBMITTER: Rossi S 

PROVIDER: S-EPMC8617364 | biostudies-literature | 2022 Jan

REPOSITORIES: biostudies-literature