Distinct Gut Microbiota Signatures in Mice Treated with Commonly Used Food Preservatives.

ABSTRACT: Diet is one of the most important factors regulating and influencing the composition of our gut microbiome, but the specific effects of commonly used antimicrobial agents i.e., food preservatives present within foods, are not completely understood. In this study, we examined the effect of the three widely used food-grade preservatives i.e., benzoic acid, potassium sorbate, and sodium nitrite, in recommended levels, on the gut microbiota diversity and composition in a mouse model. The analysis of β-diversity reveals distinct signatures of the gut microbiota between mice consuming different preservatives. Further analyses of α-diversity indices also show that the three preservatives induce specific patterns of microbial diversity, with diversity being lowest in mice consuming potassium sorba

SUBMITTER: Nagpal R 

PROVIDER: S-EPMC8617889 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature