New Models to Predict the Acute and Chronic Toxicities of Representative Species of the Main Trophic Levels of Aquatic Environments.
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ABSTRACT:
SUBMITTER: Toma C
PROVIDER: S-EPMC8618112 | biostudies-literature | 2021 Nov
REPOSITORIES: biostudies-literature
Publications
New Models to Predict the Acute and Chronic Toxicities of Representative Species of the Main Trophic Levels of Aquatic Environments.
Toma Cosimo C Cappelli Claudia I CI Manganaro Alberto A Lombardo Anna A Arning Jürgen J Benfenati Emilio E
Molecules (Basel, Switzerland) 20211119 22
To assess the impact of chemicals on an aquatic environment, toxicological data for three trophic levels are needed to address the chronic and acute toxicities. The use of non-testing methods, such as predictive computational models, was proposed to avoid or reduce the need for animal models and speed up the process when there are many substances to be tested. We developed predictive models for <i>Raphidocelis subcapitata</i>, <i>Daphnia magna</i>, and fish for acute and chronic toxicities. The ...[more]
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