Feature-Based Molecular Networking-An Exciting Tool to Spot Species of the Genus <i>Cortinarius</i> with Hidden Photosensitizers.

ABSTRACT: Fungi have developed a wide array of defense strategies to overcome mechanical injuries and pathogen infections. Recently, photoactivity has been discovered by showing that pigments isolated from Cortinarius uliginosus produce singlet oxygen under irradiation. To test if this phenomenon is limited to dermocyboid Cortinarii, six colourful Cortinarius species belonging to different classical subgenera (i.e., Dermocybe, Leprocybe, Myxacium, Phlegmacium, and Telamonia) were investigated. Fungal extracts were explored by the combination of in vitro photobiological methods, UHPLC coupled to high-resolution tandem mass spectrometry (UHPLC-HRMS²), feature-based molecular networking (FBMN), and metabolite dereplication techniques. The fung

SUBMITTER: Hammerle F 

PROVIDER: S-EPMC8619139 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature