Breast Cancer Subtypes and Mortality of Breast Cancer Patients With Brain Metastasis at Diagnosis: A Population-Based Study.

ABSTRACT:

Background

Brain metastasis is an important cause of breast cancer-related death.

Aim

We evaluated the relationships between breast cancer subtype and prognosis among patients with brain metastasis at the initial diagnosis.

Methods

The Surveillance, Epidemiology, and End Results database was searched to identify patients with brain metastasis from breast cancer between 2010 and 2015. Multivariable Cox proportional hazard models were used to identify factors that were associated with survival among patients with initial brain metastases. The Kaplan-Meier method was used to compare survival outcomes according to breast cancer subtype.

Results

Among 752 breast cancer patients with brain metastasis at diagnosis, 140 patients (18.6%) underwent primary surgery and 61

SUBMITTER: He DJ 

PROVIDER: S-EPMC8619743 | biostudies-literature | 2021 Jan-Dec

REPOSITORIES: biostudies-literature