Psychiatric Comorbidities in 1p36 Deletion Syndrome and Their Treatment-A Case Report.

ABSTRACT: 1p36 deletion syndrome represents the most common terminal deletion observed in humans. Major clinical findings comprise developmental delay/intellectual disability, poor or absent expressive language, congenital central muscular hypotonia, brain anomalies, brachydactyly/camptodactyly, short feet, and characteristic facial features like straight eyebrows, deep-set eyes, and midface hypoplasia. So far, there is very limited knowledge about comorbid psychiatric disorders and their effective treatment in this special population. To fill this gap, this case report presents an initially four-year-old girl with 1p36.33-1p36.32 deletion, moderate intellectual disability, insomnia, oppositional-defiant disorder and attention deficit/hyperactivity disorder covering a period of time of about 1.5 yea

SUBMITTER: Briegel W 

PROVIDER: S-EPMC8619815 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature