Synthesis and Fungicidal Activity of Hydrated Geranylated Phenols against Botrytis cinerea.

ABSTRACT: Botrytis cinerea is a ubiquitous fungus that affects hundreds of plants, resulting in economic losses to the horticulture and fruit industry. The search for new antifungal agents is a matter of current interest. Thus, in this work a series of geranylated phenols in which the side alkyl chain has been hydrated have been synthesized, and their activity against B. cinerea has been evaluated. The coupling of phenol and geraniol has been accomplished under microwave irradiation obtaining the highest reaction yields in the shortest reaction times. Hydration of the side chain was carried out in dioxane with p-toluenesulfonic acid polymer-bound as the catalyst. All synthesized compounds were tested against B. cinerea using the growth inhibition assay and EC₅₀

SUBMITTER: Soto M 

PROVIDER: S-EPMC8620067 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature