Identification of potential endometriosis biomarkers in peritoneal fluid and blood plasma via shotgun lipidomics.

ABSTRACT: Endometriosis is a recurrent and benign gynecological disorder, defined by the ectopic presence of endometrium. About 10% of reproductive-aged women suffer from endometriosis. There are no non-invasive or minimally invasive tests available in clinical practice to accurately diagnose endometriosis today. Here, we present our efforts to determine the diagnostic accuracy of biomarkers in peritoneal fluid and blood plasma using flow injection analysis with electrospray ionization tandem mass spectrometry (ESI-MS/MS) in 70 women with endometriosis and 20 women from a control group. The presence of endometriosis was confirmed by surgical findings and post-operative pathological examination. A qualitative and quantitative evaluation of the lipids in peritoneal fluids and blood plasma was carried

SUBMITTER: Starodubtseva N 

PROVIDER: S-EPMC8620138 | biostudies-literature | 2019 Aug

REPOSITORIES: biostudies-literature