Analysis of Differentially Expressed Genes That Aggravate Metabolic Diseases in Depression.

ABSTRACT: Depression is considered the second leading cause of the global health burden after cancer. It is recognized as the most common physiological disorder. It affects about 350 million people worldwide to a serious degree. The onset of depression, inadequate food intake, abnormal glycemic control and cognitive impairment have strong associations with various metabolic disorders which are mediated through alterations in diet and physical activities. The regulatory key factors among metabolic diseases and depression are poorly understood. To understand the molecular mechanisms of the dysregulation of genes affected in depressive disorder, we employed an analytical, quantitative framework for depression and related metabolic diseases. In this study, we examined datasets containing patients with d

SUBMITTER: Bhadra S 

PROVIDER: S-EPMC8620538 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature