Accumulation and Effect of Silver Nanoparticles Functionalized with Spirulina platensis on Rats.

ABSTRACT: The effect of unmodified and functionalized Spirulina platensis biomass silver nanoparticles on rats during prolonged oral administration was assessed. Silver nanoparticles were characterized by using transmission electron microscopy, while their uptake by the biomass was confirmed using scanning electron microscopy and energy dispersive analysis. The content of silver in the different organs of rats after a period of administration (28 days) or after an additional clearance period (28 days) was ascertained by using neutron activation analysis. In animals administrated with the unmodified nanoparticles, the highest content of silver was determined in the brain and kidneys, while in animals administrated with AgNP-Spirulina, silver was mainly accumulated in the brain and testicles. A

SUBMITTER: Rudi L 

PROVIDER: S-EPMC8620753 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature