Urinary Metabolomic Profile of Neonates Born to Women with Gestational Diabetes Mellitus.

ABSTRACT: Gestational diabetes mellitus (GDM) is one of the most frequent pregnancy complications with potential adverse outcomes for mothers and newborns. Its effects on the newborn appear during the neonatal period or early childhood. Therefore, an early diagnosis is crucial to prevent the development of chronic diseases later in adult life. In this study, the urinary metabolome of babies born to GDM mothers was characterized. In total, 144 neonatal and maternal (second and third trimesters of pregnancy) urinary samples were analyzed using targeted metabolomics, combining liquid chromatographic mass spectrometry (LC-MS/MS) and flow injection analysis mass spectrometry (FIA-MS/MS) techniques. We provide here the neonatal urinary concentration values of 101 metabolites for 26 newborns born to GDM mo

SUBMITTER: Herrera-Van Oostdam AS 

PROVIDER: S-EPMC8621167 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature