Cerium(IV) and Iron(III) Oxides Nanoparticles Based Voltammetric Sensor for the Sensitive and Selective Determination of Lipoic Acid.

ABSTRACT: A novel voltammetric sensor based on CeO2·Fe2O3 nanoparticles (NPs) has been developed for the determination of lipoic acid, playing an essential role in aerobic metabolism in the living organism. Sensor surface modification provides a 5.6-fold increase of the lipoic acid oxidation currents and a 20 mV anodic shift of the oxidation potential. The best voltammetric parameters have been obtained for the 0.5 mg mL-1 dispersion of CeO2·Fe2O3 NPs. Scanning electron microscopy (SEM) confirms the presence of spherical NPs of 25-60 nm, and their aggregates evenly distributed on the electrode surface and formed porous coverage. This leads to the 4.4-fold increase of the effective surface area vs. bare glassy carbon electrode (GCE). The sensor shows a significantly higher electron transfer rate. Ele

SUBMITTER: Ziyatdinova G 

PROVIDER: S-EPMC8621773 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature