The 4-Year Experience with Implementation and Routine Use of Pathogen Reduction in a Brazilian Hospital.

ABSTRACT: (1) Background: We reviewed the logistics of the implementation of pathogen reduction (PR) using the INTERCEPT Blood System™ for platelets and the experience with routine use and clinical outcomes in the patient population at the Sírio-Libanês Hospital of São Paulo, Brazil. (2) Methods: Platelet concentrate (PC), including pathogen reduced (PR-PC) production, inventory management, discard rates, blood utilization, and clinical outcomes were analyzed over the 40 months before and after PR implementation. Age distribution and wastage rates were compared over the 10 months before and after approval for PR-PC to be stored for up to seven days. (3) Results: A 100% PR-PC inventory was achieved by increasing double apheresis collections and production of double doses using pools of two single aph

SUBMITTER: Fachini RM 

PROVIDER: S-EPMC8621808 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature