The vaccination threshold for SARS-CoV-2 depends on the indoor setting and room ventilation.

ABSTRACT:

Background

Effective vaccines are now available for SARS-CoV-2 in the 2nd year of the COVID-19 pandemic, but there remains significant uncertainty surrounding the necessary vaccination rate to safely lift occupancy controls in public buildings and return to pre-pandemic norms. The aim of this paper is to estimate setting-specific vaccination thresholds for SARS-CoV-2 to prevent sustained community transmission using classical principles of airborne contagion modeling. We calculated the airborne infection risk in three settings, a classroom, prison cell block, and restaurant, at typical ventilation rates, and then the expected number of infections resulting from this risk at varying percentages of occupant immunity.

Results

We estimate the setting-specific immunity threshold

SUBMITTER: Mikszewski A 

PROVIDER: S-EPMC8622112 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature