Baseline Drug Treatments as Indicators of Increased Risk of COVID-19 Mortality in Spain and Italy.

ABSTRACT: This study aims to identify baseline medications that, as a proxy for the diseases they are dispensed for, are associated with increased risk of mortality in COVID-19 patients from two regions in Spain and Italy using real-world data. We conducted a cross-country, retrospective, observational study including 8570 individuals from both regions with confirmed SARS-CoV-2 infection between 4 March and 17 April 2020, and followed them for a minimum of 30 days to allow sufficient time for the studied event, in this case death, to occur. Baseline demographic variables and all drugs dispensed in community pharmacies three months prior to infection were extracted from the PRECOVID Study cohort (Aragon, Spain) and the Campania Region Database (Campania, Italy) and analyzed using logistic regression

SUBMITTER: Bliek-Bueno K 

PROVIDER: S-EPMC8623536 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature