Single-Cell Multiomics Analysis for Drug Discovery.

ABSTRACT: Given the heterogeneity seen in cell populations within biological systems, analysis of single cells is necessary for studying mechanisms that cannot be identified on a bulk population level. There are significant variations in the biological and physiological function of cell populations due to the functional differences within, as well as between, single species as a result of the specific proteome, transcriptome, and metabolome that are unique to each individual cell. Single-cell analysis proves crucial in providing a comprehensive understanding of the biological and physiological properties underlying human health and disease. Omics technologies can help to examine proteins (proteomics), RNA molecules (transcriptomics), and the chemical processes involving metabolites (metabolomics) in

SUBMITTER: Nassar SF 

PROVIDER: S-EPMC8623556 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature