Personalised Medicine for Tuberculosis and Non-Tuberculous Mycobacterial Pulmonary Disease.

ABSTRACT: Personalised medicine, in which clinical management is individualised to the genotypic and phenotypic data of patients, offers a promising means by which to enhance outcomes in the management of mycobacterial pulmonary infections. In this review, we provide an overview of how personalised medicine approaches may be utilised to identify patients at risk of developing tuberculosis (TB) or non-tuberculous mycobacterial pulmonary disease (NTM-PD), diagnose these conditions and guide effective treatment strategies. Despite recent technological and therapeutic advances, TB and NTM-PD remain challenging conditions to diagnose and treat. Studies have identified a range of genetic and immune factors that predispose patients to pulmonary mycobacterial infections. Molecular tests such as nucleic acid

SUBMITTER: Kumar K 

PROVIDER: S-EPMC8624359 | biostudies-literature | 2021 Oct

REPOSITORIES: biostudies-literature