Activated Carbon Fiber Cloth/Biomimetic Apatite: A Dual Drug Delivery System.

ABSTRACT: A biomaterial that is both bioactive and capable of controlled drug release is highly attractive for bone regeneration. In previous works, we demonstrated the possibility of combining activated carbon fiber cloth (ACC) and biomimetic apatite (such as calcium-deficient hydroxyapatite (CDA)) to develop an efficient material for bone regeneration. The aim to use the adsorption properties of an activated carbon/biomimetic apatite composite to synthetize a biomaterial to be used as a controlled drug release system after implantation. The adsorption and desorption of tetracycline and aspirin were first investigated in the ACC and CDA components and then on ACC/CDA composite. The results showed that drug adsorption and release are dependent on the adsorbent material and the drug polarity/hydrophi

SUBMITTER: Olivier F 

PROVIDER: S-EPMC8624510 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature