Prognostic Impact of Sleep Patterns and Related-Drugs in Patients with Heart Failure.

ABSTRACT: Sleep disturbances are frequent among patients with heart failure (HF). We hypothesized that self-reported sleep disturbances are associated with a poor prognosis in patients with HF. A longitudinal study of 119 patients with HF was carried out to assess the association between sleep disturbances and the occurrence of major cardiovascular events (MACE). All patients with HF completed self-administered questionnaires on sleepiness, fatigue, insomnia, quality of sleep, sleep patterns, anxiety and depressive symptoms, and central nervous system (CNS) drugs intake. Patients were followed for a median of 888 days. Cox models were used to estimate the risk of MACE associated with baseline sleep characteristics. After adjustment for age, the risk of a future MACE increased with CNS drugs intake,

SUBMITTER: Bughin F 

PROVIDER: S-EPMC8625841 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature