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Predominance of non-Streptococcus mutans bacteria in dental biofilm and its relation to caries progression.


ABSTRACT: This study aims to assess differences in biofilm bacterial composition between patients with low and high caries. Patients without a medical problem and with no history of antibiotic use, mouth wash or fluoride application in the previous 3 months were recruited. Caries was recorded at cavitation level; score was calculated by a national mean (dmft of 4.8 and DMFT of 2.7). Pooled biofilm samples were collected from mesial, distal, buccal, lingual, and occlusal surfaces. Based on caries experience, individuals were classified into low and high caries and both groups were compared regarding bacteria identified using 16S rRNA gene sequencing, and molecular phylogenetic analysis of the isolates was performed. A total of twenty seven randomly selected samples with low (n = 13) and

SUBMITTER: AlEraky DM 

PROVIDER: S-EPMC8626303 | biostudies-literature | 2021 Dec

REPOSITORIES: biostudies-literature