Primary hyperoxaluria diagnosed after kidney transplantation: a case report and literature review.

ABSTRACT:

Background

Primary hyperoxaluria (PH) is a rare inherited autosomal recessive disease caused by disturbed glyoxylate metabolism. The disease is characterized by calcium oxalate crystal deposition in various organs, especially in the kidney. Due to the lack of current understanding of PH, nearly all patients are only initially diagnosed with PH when recurrent lithiasis and progressive end-stage renal disease occur. Many cases are not diagnosed in patients until renal allograft insufficiency occurs after renal transplantation. This case report and literature review aim to emphasize the need for careful pre-transplant PH screening of patients with bilateral nephrocalcinosis or nephrolithiasis.

Case presentation

Renal allograft insufficiency was diagnosed as PH after kidney tran

SUBMITTER: Cai Z 

PROVIDER: S-EPMC8626922 | biostudies-literature | 2021 Nov

REPOSITORIES: biostudies-literature